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Venkateswara Rao, B.
- Sensitivity Analysis Based Optimal Location and Tuning of Static Var Compensator Using Firefly Algorithm
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Affiliations
1 GITAM University, Visakhapatnam, Andhra Pradesh, IN
1 GITAM University, Visakhapatnam, Andhra Pradesh, IN
Source
Indian Journal of Science and Technology, Vol 7, No 8 (2014), Pagination: 1201-1210Abstract
This paper presents a new Meta heuristic optimization algorithm called firefly algorithm (FA) used to solve the multi objective optimal power flow to identify the optimal setting of Static VAR Compensator (SVC) and optimal location is identified by using sensitivity analysis when the system is operating under normal and overloaded conditions. Sensitivity analysis based Voltage collapse proximity Index is proposed for placing the SVC at appropriate location under normal and over loaded conditions. Once the location to install SVC is identified, the optimal allocation of SVC is determined through firefly algorithm based A multi-criterion objective function comprising of four objectives minimize total power loss, minimize total voltage magnitude deviations, minimize the fuel cost of total generation and minimize the branch loading to obtain the optimal power flow. Simulations have been implemented in MATLAB and the IEEE 14-bus, IEEE 30-bus and IEEE 57-bus systems have been used as a case study. The results we have obtained indicate that installing SVC can significantly enhance the voltage stability of power system. Also for the purpose of comparison the proposed technique was compared with another optimization technique namely Genetic Algorithm (GA). The results we have obtained indicate that FA is an easy to use, robust, and powerful optimization technique compared with GA.Keywords
Firefly Algorithm, Optimization, Static VAR Compensator, VCPI- Simultaneous UV Spectrophotometric Method for the Determination of Tenofovir, Efavirenz and Lamivudine in Bulk and Combined Dosage Form
Abstract Views :229 |
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Authors
Affiliations
1 Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Chowdavaram, Guntur – 19, Andhra Pradesh, IN
1 Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Chowdavaram, Guntur – 19, Andhra Pradesh, IN
Source
Asian Journal of Pharmaceutical Analysis, Vol 6, No 4 (2016), Pagination: 253-258Abstract
The aim of the present work is to develop a simple, accurate, precise and reproducible UV spectrophotometric method for the simultaneous determination of Tenofovir, Efavirenz and Lamivudine in bulk and pharmaceutical dosage form. The stock solutions of the standard drugs were prepared in methanol followed by the further required dilutions with distilled water. This method involves the formation and solving of simultaneous equations at 260nm, 347nm and 272 nm, as absorbance maxima of Tenofovir, Efavirenz and Lamivudine respectively. Beer's law obeyed the concentration range of 10 - 40mcg/mL, 5 - 20 mcg/mL and 5 - 20 mcg/mL for Tenofovir, Efavirenz and Lamivudine respectively. The results of analysis were validated statistically and by recovery studies. The % RSD for the recovery study was less than 2. The proposed method can be effectively used for the simultaneous estimation of these three drugs in bulk and combined tablet dosage form.Keywords
Tenofovir, Efavirenz and Lamivudine, Simultaneous Equation Method, Method Validation.- Tolerance Allocation and Analysis of Precision Aerospace Components
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Authors
Affiliations
1 Defence Research & Development Laboratory, Hyderabad - 500058, IN
1 Defence Research & Development Laboratory, Hyderabad - 500058, IN
Source
International Journal of Engineering Research, Vol 5, No SP 2 (2016), Pagination: 337-344Abstract
Tolerancing plays a vital role in design process. For aerospace components, any deviation beyond allowable limit can result in catastrophic failure.In this work, toleranceanalysis is performed to address axis misalignment due to tolerance stacking in flight vehicle components and allocation of optimal tolerances for minimum cost obtained using DFM analysis.Keywords
Geometric Dimensioning & Tolerancing (GD&T), Tolerance Allocation, Tolerance Analysis (TA), Worst-Case TA, Statistical TA, Design for Manufacture (DFM).- FTIR and Ultrasonic Studies on Molecular Interactions of Ester with Butanol in the Temperature Range 303.15-318.15 K
Abstract Views :264 |
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Authors
Affiliations
1 Department of Engineering Chemistry, College of Engineering, Andhra University, Visakhapatnam-530 003, IN
2 Department of Civil Engineering, College of Engineering, Andhra University, Visakhapatnam-530 003, IN
1 Department of Engineering Chemistry, College of Engineering, Andhra University, Visakhapatnam-530 003, IN
2 Department of Civil Engineering, College of Engineering, Andhra University, Visakhapatnam-530 003, IN
Source
Current Science, Vol 113, No 08 (2017), Pagination: 1553-1559Abstract
Ultrasonic velocity, viscosity and density of ethyl oleate in butanol have been determined at various temperatures in the range 303.15-318.15 K. These data are used to estimate adiabatic compressibility, intermolecular free length and acoustic impedance, molar volume and free volume along with their excess values. The observed variations in these parameters with different concentrations and temperatures are discussed in terms of the intermolecular interactions between the unlike molecules of the binary mixtures.Keywords
Butanol, Ethyl Oleate, Density, Ultrasonic Speed, Viscosity.References
- Narendra, K., Srinivasu, C. H. and Fakruddin, S. K., Excess parameters of binary mixtures of anisaldehyde with o-cresol, m-cresol and p-cresol at T = (303.15, 308.15, 313.15, and 318.15) K. J. Chem. Thermodyn., 2011, 43, 1604–1611.
- Ali, A., Yasmin, A. and Nain, A. K., Study of intermolecular interactions in binary liquid mixtures through ultrasonic speed measurement. Indian J. Pure Appl. Phys., 2002, 40, 315–322.
- Fakruddin, S. K., Srinivasu, C. H. and Narendra, K., Theoretical studies of ultrasonic velocities in binary liquid mixtures of quinoline at different temperatures. J. Chem. Pharm. Res., 2012, 4, 1799–1806.
- Kumara Sastry, S. V., Shaik Babu, Tiong, H. S. and Sreehari Sastry, S., Ultrasonic investigation of molecular interactions in ternary mixtures at 303 K. J. Chem. Pharm. Res., 2012, 4, 2122– 2125.
- Instruction Manuals for Instrument Ultrasonic Interferometer Model F-05 and for Constant Temperature Water Bath Supplied along with the Instrument. Mittal Enterprises.
- Nikam, P. S., Mahale, T. R. and Hasan, M., Molecular interaction in mixtures of dimethyl sulfoxide with some alkanols – an ultrasonic study. J. Acoust. Acta, 1998, 84, 579–587.
- Nikam, P. S., Jadhav, M. C. and Hasan, M. J., Volumetric, viscometric and ultrasonic behaviour of dimethyl sulfoxide with normal alcohols at 308.15 K. J. Mol. Liq., 1998, 76, 1–11.
- Nikam, P. S., Mahale, T. R. and Hasan, M., Molecular interactions in binary mixtures of ethyl acetate with 1-pentanol, 1-hexanol, 3,5,5-trimethyl hexanol,1-octanol and 1-decanol at 298.15, 303.15 and 308.15 K: an ultrasonic study. Indian J. Pure Appl. Phys., 1999, 37, 92–96.
- Kannappan, V., Jayasanthi, R. and Malar, E. J. P., Ultrasonic studies on charge transfer complexes of cyclo alkanones with chloroform in n-hexane solutions. J. Phys. Chem. Liq., 2002, 40, 507– 525.
- Palani, R., Geetha, A., Saravanan, S. and Sunil, D. T., Physicochemical behaviour of binary liquid mixtures of some monohydroxy alcohols with DMSO as common solvent. Rasayan J. Chem., 2008, 1, 481–488.
- Nain, A. K., Srivastava, T., Pandey, J. D. and Gopal, S., Densities, ultrasonic speeds and excess properties of binary mixtures of methyl acrylate with 1-butanol, or 2-butanol, or 2-methyl-1propanol, or 2-methyl-2-propanol at temperatures from 288.15 to 318.15 K. J. Mol. Liq., 2009, 149, 9–17.
- Ali, A., Tasneem, S. and Nabi, F., Volumetric, viscometric, and ultrasonic properties of liquid mixtures of cyclohexane with alkanols at different temperatures. J. Naturforsch, 2010, 65, 749–760.
- Santhi, N., Sabarathinam, P. L., Alamelumangai, G., Madhumitha, J. and Emayavaramban, M., Ultrasonic study of molecular interaction in binary liquid mixtures of n-hexane with alcohols. Int. Lett. Chem., Phys. Astron., 2012, 5, 59–71.
- Dunitrescu, V. and Pantea, O., Viscosities of binary mixtures of toluene with butan-1-ol and 2-methylpropan-2-ol. J. Serb. Chem. Soc., 2005, 70, 1313–1323.
- Elangovan, S. and Mullainathan, S., Ultrasonic studies of brompheniramine with 1-butanol at 303, 308 and 313 K. Elixir Ultrasonics, 2013, 58A, 15048–15052.
- Papari, M. M., Ghodrati, H., Fadaei, F., Sadeghi, R., Behrouz, S., Soltani Rad, M. N. and Moghadasi, J., Volumetric and ultrasonic study of mixtures of 2-phenylethanol with 1-butanol, 2-butanol, and 2-methyl-1-butanol at T = (298.15–323.15) K and atmospheric pressure: measurement and prediction. J. Mol. Liq., 2013, 180, 121–128.
- Kondaiah, M., Sreekanth, K., Sravana Kumar, D. and Krishna Rao, D., Acoustic and volumetric properties of mixture of (N,Ndimethylacetamide + ethyl acrylate) with 1-butanol or iso-butanol or t-butanol at 308.15 K. J. Thermodyn., 2014, 1–9; Article ID: 124012.
- Singh, K. P. and Mishra, S., Acoutical and thermodynamical study of binary mixture of poly (ethylene glycol) dimethyl ether 250 (PEGDME 250) with 1-propanol and 1-butanol at varying temperatures. Int. J. Chem. Eng. Appl. Sci., 2014, 4, 5–11.
- Suryanarayana, C. V., Ultrasound as a probe for assessing the internal pressure and molar cohesive energy of a liquid system: a new model. Ultrasonics, 1993, 31(4), 281–287.
- Jacobson, B., Intermolecular free length in the liquid state I adiabatic and isothermal compressibilities. Acta Chem. Scand. (Denmark), 1952, 6, 1485–1487.
- Karunakar, T., Srinivasu, C. H. and Narendra, K., Thermo acoustic and infrared study of molecular interactions in binary mixture aniline + 1-butanol. Res. Rev.: J. Pure Appl. Phys., 2013, 1, 5–15.
- Sivagurunathan, P., Dharmalingam, K. and Ramachandran, K., FTIR study of hydrogen bonding between acrylic esters and alcohols. J. Solut. Chem., 2006, 35, 1467–1475.
- Smith, H. F. and Rosenberg, A. S., Investigation of aliphatic ester–alcohol hydrogen bonding by infrared spectroscopy: determination of equilibrium and thermodynamic constant. J. Chem. Soc., Part V, 1963, 5391–5395.
- Rajalakshmi, S., Molecular interaction between aliphatic alcohols with n-methylacetamide: an FTIR study. Int. J. Recent Sci. Res., 2012, 3, 12–19.
- Nain, A. K., Ultrasonic and viscometric study of molecular interactions in binary mixtures of aniline with 1-propanol, 2-propanol, 2-methyl-1-propanol, and 2-methyl-2-propanol at different temperatures. Fluid Phase Equil., 2007, 259, 218–227.
- A Novel RP-HPLC Method Development and Validation for the Determination of Pioglitazone and Glimepiride in Bulk and Pharmaceutical Formulations
Abstract Views :316 |
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Authors
Affiliations
1 Department of Pharmaceutical Analysis, Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Chowdavaram, Guntur, Andhra Pradesh, IN
1 Department of Pharmaceutical Analysis, Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Chowdavaram, Guntur, Andhra Pradesh, IN
Source
Asian Journal of Pharmaceutical Analysis, Vol 7, No 3 (2017), Pagination: 145-150Abstract
A simple, precise, accurate, reproducible and economical stability- indicating reverse phase liquid chromatography method was developed and validated for the quantitative simultaneous estimation of Pioglitazone and Glimepiride in marketed formulations. Estimation of drugs in this combination was done with a C18 column (Kromasil 100-5 column, 250mm x 4.6mm) using mobile phase of composition phosphate buffer pH 7: Acetonitrile in ratio 60:40 v/v. The flow rate was 0.8 ml/min and the effluents were monitored at 230 nm. The retention time of Pioglitazone and Glimepiride were 6.71 min and 8.38 min respectively. The method was found to be linear over a range of 10-50 μg/ml for Pioglitazone and 3-15 μg/ml for Glimepiride. The established method proved as reproducible one with a % RSD value of less than 2 and having the robustness and accuracy within the specified limits. Assay of marketed formulation was determined and find with 96% and 98% for Pioglitazone and Glimepiride respectively. The method was validated according to the guidelines of International Council for Harmonization (ICH) and was successfully employed in the estimation of commercial formulations. This liquid chromatographic method can be applied for the qualitative and quantitative determination of selected drugs by the modern chemist.Keywords
Pioglitazone, Glimepiride, RP-HPLC and Method validation.References
- Martindale (The complete drug reference) 2005, 34th edition, 632 and 655.
- Merck Index 14th edition, 2006, 9151 and 3568.
- Indian Pharmacopeia 2014, 7th edition, Vol 2 and 3, 1652 and 2834.
- K. S. Lakshmi T. Rajesh. Development and Validation of RPHPLC Method for Simultaneous Determination of Glipizide, Rosiglitazone, Pioglitazone, Glibenclamide and Glimepiride in pharmaceutical dosage forms and human plasma. Journal of the Iranian Chemical Society. 8(1); 2011: 31-37.
- Sami El Deeb, Udo Schepers, Hermann Watzig. Fast HPLC Method for the Determination of Glimepiride, Glibenclamide, and Related Substances using Monolithic Column and Flow Program.Journal of Separation Science. 29(11); 2006: 1571-1577.
- P. K. Sahoo, R. Sharma, and S. C. Chaturvedi. Simultaneous Estimation of Metformin Hydrochloride and Pioglitazone Hydrochloride by RPHPLC Method from Combined Tablet Dosage Form. Indian Journal of Pharmaceutical Sciences. 70(3); 2008: 383–386.
- Karthik Arumugam, Subramanian Ganesan, Chamallapudi Mallikharjuna Rao, Nayanabhirama Udupa. Simultaneous Determination of Pioglitazone and Glimepiride in Bulk Drug and Pharmaceutical Dosage Form by RP-HPLC Method. Pakistan Journal of Pharmaceutical Sciences. 21(4); 2008: 421-425.
- Gadapa Nirupa, and Upendra M. Tripathi. RP-HPLC Analytical Method Development and Validation for Simultaneous Estimation of Three Drugs: Glimepiride, Pioglitazone, and Metformin and its Pharmaceutical Dosage Forms. Journal of Chemistry. 2013: 1-8.
- D. Adukondalu, P. S. Malathy, J. V. Rao, and Y. M. Rao, Development and Validation of HPLC Method for Detection of Pioglitazone hydrochloride in Dosage Forms. International Journal of Pharmacy and Biological Sciences. 1(4); 2011: 474–478.
- D. B. Pathare, A. S. Jadhav, and M. S. Shingare, RP-LC Determination of the cis-isomer of Glimepiride in a Bulk Drug Substance. Chromatographia. 66(7-8); 2007: 639–641.
- N. Satheeshkumar , S. Shantikumar, R. Srinivas. Pioglitazone: A review of analytical methods. Journal of Pharmaceutical Analysis. 4(5); 2014: 295–302.
- Deepti Jain, Surendra Jain, Deepak Jain, Maulik Amin. Simultaneous Estimation of Metformin Hydrochloride, Pioglitazone Hydrochloride, and Glimepiride by RP-HPLC in Tablet Formulation. Journal of Chromatographic Science. 46(6); 2008: 501-504.
- G. Navaneethan, K. Karunakaran and K. P. Elango. Simultaneous Estimation of Pioglitazone, Glimepiride and Glimepiride Impurities in Combination Drug Product by a Validated StabilityIndicating RP-HPLC Method. Journal of Chilean of Chemical Society. 56(3); (2011): 815-818.
- M Suchitra, D Sunitha, C Parthiban, B Siddartha and C Madhavi. Method Development and Validation of Metforminm, Glimepiride and Pioglitazone in Tablet Dosage Forms by RP-HPLC. International Research Journal of Pharmacy. 4(8); 2013: 250-254.
- Rani G Shobha, Lohitha M, Preethi P Jaya, Madhavi R, Sunisitha B and Mounika D. Glimepiride Review of Analytical Methods. Asian Journal of Pharmaceutical Analysis. 4(4); 2014: 178-182.
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- M. S. V. Sakuntala, S. V. U. M. Prasad, S. Sri Devi, S. Kishore Yadav and K. Srinivas Reddy. A RP- HPLC Method Development and Validation for the Simultaneous Estimation of Glimepiride and Pioglitazone HCl in Tablet Dosage Forms. Journal of Chemical and Pharmaceutical Research. 4(1): 2012:154-159.
- Ravi Sharma, Gagan Sharma and Darpan chopra, Analytical Method Development and Validation for the Simultaneous Estimation of Glimepiride and Pioglitazone in Tablet Dosage Form by RP-HPLC. International Journal of Pharmaceutical Sciences and Research. 2(3); 2012: 637-641.
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- Praveen Kumar Reddy B, Boopathy D, Bibin Mathew, Prakash M, Perumal P. Method Development and Validation of Simultaneous Determination of Pioglitazone and Glimepiride in Pharmaceutical Dosage Form by RP-HPLC. International Journal of Chem Tech Research. 2(1); 2010: 50-53.
- Kalyankar. T.M, Badguja. M.R, Mitkare S.S and Kakde R.B. HPTLC Method for Simultaneous Analysis of Pioglitazone HCL and Glimepiride in Pharmaceutical Preparations. Journal of Pharmacy Research. 3(12); 2010: 3118-3120.
- An Optimization Procedure for Dropping Information Deduplication in Crossbreed Cloud Technique
Abstract Views :219 |
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Authors
Affiliations
1 Department of Computer Science and Engineering, Institute of Aeronautical Engineering, Dundigal − 500043, Hyderabad, Telangana, IN
1 Department of Computer Science and Engineering, Institute of Aeronautical Engineering, Dundigal − 500043, Hyderabad, Telangana, IN
Source
Indian Journal of Science and Technology, Vol 11, No 44 (2018), Pagination: 1-8Abstract
Objectives: In computing, facts/data deduplication is a particular statistics firmness method for removing reproduction copy of repeating records. Intelligent compression or single-instance storage technique make sure that merely single sole request of information is retained on storage space media, such as disk, flash or tape. Unneeded data blocks are replaced with a pointer to the sole data copy. Methods: This study introduces focus on comparing the clouds via authorization steps, which incorporates file token technology and proportion token generation, in competition. To the convergent encryption and document add steps. We compare the overhead through using quite a lot of distinctive reasons. Findings: In cloud computing reproduction copies of repeat facts within the cloud referred to as Data Deduplication, and broadly used in cloud garage to decrease the amount of garage space and stay bandwidth. Data deduplication removes reproduction copies of equal documents can be existed in Cloud, if so best one reproduction is maintained and replacing the alternative copies with the original reproduction. To defend the privateness of sensitive Information on similar instance as maintaining deduplication, security algorithm is proposed for statistics safety. Application: We enforce a prototype of our proposed legal replica test scheme and behavior tested experiments the usage of our prototype. It shows planned legal duplicate test scheme incurs minimum overhead in comparison to ordinary operations.References
- Jin Li, Yan Kit Li, Xiaofeng Chen, Patrick P. C. Lee, Wenjing Lou. A hybrid cloud approach for secure authorized de duplication, IEEE Transactions on Parallel and Distributed System. 2015; 26(5):1−12. https://doi.org/10.1109/TPDS.2014.2318320.
- Kakariya G, Rangdale S. A hybrid cloud approach for secure authorized de duplication, International Journal of Computer Engineering and Applications. 2014; 8(1): 1−7.
- Leavitt N. Hybrid clouds move to the forefront, Computer. 2013; 46(5):15−18. https://www.researchgate.net/publication/ 260584421_Hybrid_Clouds_Move_to_the_Forefront.
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- Douceur JR, Adya A, Bolosky WJ, Simon D, Theimer M. Reclaiming space from duplicate files in a server less distributed file system. In: ICDCS; 2002. p. 617–24.